Bright Life International, Inc. is a leading biotech company that manufactures and distributes the highest quality products for life science research. Partnering with the world class biotech industry suppliers in the fields of molecular biology, immunology, cell biology and tumor biology etc., we supply the most advanced service with a wide range of antibodies to meet the growing needs of Chinese and US professionals.

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Resistance to Chemotherapy-Multidrug Resistance Antibodies

Chemotherapy has many advances in the treatment of disseminated tumors and although it is quite effective in treating certain cancers, most other types of cancer respond to chemotherapy poorly or partially. Failure of chemotherapeutic regimen may be due to different factors including the inability of the drug to reach the tumor site. Tumor cell that are insensitive to anticancer drugs frequently have a multidrug resistance MDR phenotype. The MRP gene product, Multidrug Resistance-associated Protein has been shown to confer a similar resistance phenotype. The understanding of these mechanisms is fundamental, thus improving the results of chemotherapy.